Dutch Studies
H. Delisle. [Foetal programming of nutrition-related chronic diseases]. Sante 2002; 12: 56-63.
K.B. Michels. Early life predictors of chronic disease. J Womens Health (Larchmt) 2003; 12: 157-161.
R.C. Painter, et al. Maternal nutrition during gestation and carotid arterial compliance in the adult offspring: the Dutch famine birth cohort. J Hypertens 2007; 25: 533-540.
T. Roseboom, et al. The Dutch famine and its long-term consequences for adult health. Early Hum Dev 2006; 82: 485-491.
T.J. Roseboom, et al. Blood pressure in adults after prenatal exposure to famine. J Hypertens 1999; 17: 325-330.
Z. Stein & M. Susser. The Dutch famine, 1944-1945, and the reproductive process. II. Interrelations of caloric rations and six indices at birth. Pediatr Res 1975; 9: 76-83.
A.W. Braam, et al. Religious denomination and depression in older Dutch citizens: patterns and models. J Aging Health 1998; 10: 483-503.

Swedish Overkalix Studies
L.O. Bygren, et al. Longevity determined by paternal ancestors' nutrition during their slow growth period. Acta Biotheor 2001; 49: 53-59.
G. Kaati, et al. Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. Eur J Hum Genet 2002; 10: 682-688.
M.E. Pembrey, et al. Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genet 2006; 14: 159-166.
P. Tinghog, et al. Migration and mortality trajectories: a study of individuals born in the rural community of Overkalix, Sweden. Soc Sci Med 2011; 73: 744-751.
G. Kaati, et al. Transgenerational response to nutrition, early life circumstances and longevity. Eur J Hum Genet 2007; 15: 784-790.
M.E. Pembrey. Male-line transgenerational responses in humans. Hum Fertil (Camb) 2010; 13: 268-271.
B.T. Heijmans, et al. The epigenome: archive of the prenatal environment. Epigenetics 2009; 4: 526-531.
B.T. Heijmans, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A 2008; 105: 17046-17049.
M.E. Pembrey. Male-line transgenerational responses in humans. Hum Fertil (Camb) 2010; 13: 268-271.

Others
G.C. Burdge, et al. Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition. PLoS One 2011; 6: e28282.
T. Delport & I. Pollard. Changing perspective on obesity: genetic and environmental health consequences in the offspring. Eubios Journal of Asian and International Bioethics 2010; 20: 170-173.
L. Gong, et al. Gestational low protein diet in the rat mediates Igf2 gene expression in male offspring via altered hepatic DNA methylation. Epigenetics 2010; 5: 619-626.
R. Lambrot, et al. Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes. Nat Commun 2013; 4: 2889.
R.A. Waterland, et al. Maternal methyl supplements increase offspring DNA methylation at Axin Fused. Genesis 2006; 44: 401-406.
G.L. Wolff, et al. Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. FASEB J 1998; 12: 949-957.

R.A. Waterland, et al. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet 2010; 6: e1001252.
J.A. Colacino, et al. Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas. Epigenetics 2012; 7: 883-891.
T. Delport & I. Pollard. Changing perspective on obesity: genetic and environmental health consequences in the offspring. Eubios Journal of Asian and International Bioethics 2010; 20: 170-173.
R. Lambrot, et al. Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes. Nat Commun 2013; 4: 2889.
G. Arakeri, et al. Cleft lip and palate: an adverse pregnancy outcome due to undiagnosed maternal and paternal coeliac disease. Med Hypotheses 2010; 75: 93-98.

Rat Nuturing
R.M. Sapolsky. Mothering style and methylation. Nat Neurosci 2004; 7: 791-792.
I.C. Weaver. Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: let's call the whole thing off. Epigenetics 2007; 2: 22-28.
I.C. Weaver, et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004; 7: 847-854.
I.C. Weaver, et al. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci 2005; 25: 11045-11054.
B.S. Wheeler, et al. Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. Genetics 2012; 190: 549-557.

Psychology and Trauma
B. Labonte, et al. Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry 2012; 69: 722-731.
P.O. McGowan, et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 2009; 12: 342-348.
B. Labonte, et al. Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry 2012; 69: 722-731.
P.G. Roma, et al. Effects of cross-fostering on cocaine-induced conditioned taste aversions in Fischer and Lewis rats. Dev Psychobiol 2007; 49: 172-179.
T.L. Roth, et al. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry 2009; 65: 760-769.
J.M. Schwarz, et al. Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. J Neurosci 2011; 31: 17835-17847.
S. Keller, et al. Increased BDNF promoter methylation in the Wernicke area of suicide subjects. Arch Gen Psychiatry 2010; 67: 258-267.
C. Ernst, et al. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry 2009; 66: 22-32.
Z. Kaminsky, et al. Epigenetics of personality traits: an illustrative study of identical twins discordant for risk-taking behavior. Twin Res Hum Genet 2008; 11: 1-11.
M. Pascual, et al. Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage. Brain Behav Immun 2011; 25 Suppl 1: S80-91.
A.W. Braam, et al. Religious denomination and depression in older Dutch citizens: patterns and models. J Aging Health 1998; 10: 483-503.
Y. Liu, et al. Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. Epigenetics 2012; 7: 735-746.
J. Elia, et al. Attention-deficit/hyperactivity disorder genomics: update for clinicians. Curr Psychiatry Rep 2012; 14: 579-589.
B.G. Dias & K.J. Ressler. Parental olfactory experience influences behavior and neural structure in subsequent generations. Nat Neurosci 2013.

Addicitive Drugs and Alcohol
J.A. Colacino, et al. Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas. Epigenetics 2012; 7: 883-891.
S.L. Youngentob & J.I. Glendinning. Fetal ethanol exposure increases ethanol intake by making it smell and taste better. Proc Natl Acad Sci U S A 2009; 106: 5359-5364.
I. Ponomarev, et al. Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. J Neurosci 2012; 32: 1884-1897.
S.L. Youngentob & J.I. Glendinning. Fetal ethanol exposure increases ethanol intake by making it smell and taste better. Proc Natl Acad Sci U S A 2009; 106: 5359-5364.
Z. Zhou, et al. Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol. Proc Natl Acad Sci U S A 2011; 108: 6626-6631.
W. Renthal, et al. Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. J Neurosci 2008; 28: 7344-7349.
P.G. Roma, et al. Effects of cross-fostering on cocaine-induced conditioned taste aversions in Fischer and Lewis rats. Dev Psychobiol 2007; 49: 172-179.
V. Nieratschker, et al. Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age. Addict Biol 2012.P.G.
Roma, et al. Effects of cross-fostering on cocaine-induced conditioned taste aversions in Fischer and Lewis rats. Dev Psychobiol 2007; 49: 172-179.
J.M. Schwarz, et al. Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. J Neurosci 2011; 31: 17835-17847.
V. Pastor, et al. Histone deacetylase inhibition decreases preference without affecting aversion for nicotine. J Neurochem 2011; 116: 636-645.
M. Pascual, et al. Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage. Brain Behav Immun 2011; 25 Suppl 1: S80-91.

Prescribed Drugs
A. Duenas-Gonzalez, et al. Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors. Cancer treatment reviews 2008; 34: 206-222.
M.M. Brouwers, et al. Hypospadias: a transgenerational effect of diethylstilbestrol? Hum Reprod 2006; 21: 666-669.
R.R. Newbold, et al. Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations. Endocrinology 2006; 147: S11-17.
M. Fukuchi, et al. Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions. Neurosci Res 2009; 65: 35-43.
T.C. Karagiannis, et al. The epigenetic modifier, valproic acid, enhances radiation sensitivity. Epigenetics 2006; 1: 131-137.
B. Monti, et al. Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection. Current molecular pharmacology 2009; 2: 95-109.
L. Travaglini, et al. Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. Int J Biochem Cell Biol 2009; 41: 225-234.
E.W. Tung & L.M. Winn. Epigenetic modifications in valproic acid-induced teratogenesis. Toxicol Appl Pharmacol 2010; 248: 201-209.

Cancer
P. Blancafort, et al. Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules. Mol Pharmacol 2013; 83: 563-576.
J.A. Colacino, et al. Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas. Epigenetics 2012; 7: 883-891.
A. Papi, et al. Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells. Anticancer Res 2010; 30: 535-540.
R. Verma, et al. In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components. Toxicol Appl Pharmacol 2011; 253: 178-187.

Disease and Miscellaneous
T. Schlinzig, et al. Epigenetic modulation at birth - altered DNA-methylation in white blood cells after Caesarean section. Acta Paediatr 2009; 98: 1096-1099.
A. Esteki-Zadeh, et al. Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity. Epigenetics 2012; 7: 585-593.
K.M. Bakulski, et al. Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex. J Alzheimers Dis 2012; 29: 571-588.
L. Gong, et al. Gestational low protein diet in the rat mediates Igf2 gene expression in male offspring via altered hepatic DNA methylation. Epigenetics 2010; 5: 619-626.

IVF
D. Lucifero, et al. Potential significance of genomic imprinting defects for reproduction and assisted reproductive technology. Hum Reprod Update 2004; 10: 3-18.
M.K. Skinner & M.D. Anway. Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors. Ann N Y Acad Sci 2005; 1061: 18-32.
M.K. Skinner, et al. Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions. Genome Biol 2012; 13: R91.
C. Feng, et al. General imprinting status is stable in assisted reproduction-conceived offspring. Fertil Steril 2011; 96: 1417-1423 e1419.
L. Li, et al. Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: a putative model for ART-conceived humans. Reprod Toxicol 2011; 32: 98-105.
H.Y. Zheng, et al. Study of DNA methylation patterns of imprinted genes in children born after assisted reproductive technologies reveals no imprinting errors: A pilot study. Exp Ther Med 2011; 2: 751-755.

Psychology/Psychiatry
H.M. Abdolmaleky, et al. Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation. Am J Med Genet B Neuropsychiatr Genet 2004; 127B: 51-59.
J. Auta, et al. DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients. Schizophr Res 2013; 150: 312-318.
A.S. Brown & E.S. Susser. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophr Bull 2008; 34: 1054-1063.
J.J. Byrnes, et al. Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function. Psychopharmacology (Berl) 2013; 227: 263-272.
L. Chouliaras, et al. Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction. Curr Alzheimer Res 2013; 10: 868-876.
L. Chouliaras, et al. Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction. Curr Alzheimer Res 2012; 9: 536-544.
T.J. Crow. 'The missing genes: what happened to the heritability of psychiatric disorders?'. Mol Psychiatry 2011; 16: 362-364.
T.J. Crow. Schizophrenia as variation in the sapiens-specific epigenetic instruction to the embryo. Clin Genet 2012; 81: 319-324.
T. Delport & I. Pollard. Changing perspective on obesity: genetic and environmental health consequences in the offspring. Eubios Journal of Asian and International Bioethics 2010; 20: 170-173.
B.G. Dias & K.J. Ressler. Parental olfactory experience influences behavior and neural structure in subsequent generations. Nat Neurosci 2014; 17: 86-96.
E. Dong, et al. Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl Psychiatry 2012; 2: e159.
J. Elia, et al. Attention-deficit/hyperactivity disorder genomics: update for clinicians. Curr Psychiatry Rep 2012; 14: 579-589.
C. Ernst, et al. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry 2009; 66: 22-32.
K. Fekete, et al. Perinatal folate supply: relevance in health outcome parameters. Maternal & child nutrition 2010; 6 Suppl 2: 23-38.
E.M. Frans, et al. Autism risk across generations: a population-based study of advancing grandpaternal and paternal age. JAMA psychiatry 2013; 70: 516-521.
D.P. Gavin & S. Akbarian. Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiol Dis 2012; 46: 255-262.

D.C. Dolinoy, et al. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci U S A 2007; 104: 13056-13061.
M.D. Anway, et al. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 2005; 308: 1466-1469.
C. Guerrero-Bosagna, et al. Environmentally induced epigenetic transgenerational inheritance of altered Sertoli cell transcriptome and epigenome: molecular etiology of male infertility. PLoS One 2013; 8: e59922.
H.D. Morgan, et al. Epigenetic inheritance at the agouti locus in the mouse. Nat Genet 1999; 23: 314-318.
A.T. Moynihan, et al. Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility. Am J Obstet Gynecol 2008; 199: 167 e161-167.
O. Pelkonen. Environmental influences on human foetal and placental xenobiotic metabolism. Eur J Clin Pharmacol 1980; 18: 17-24.
M.K. Skinner & M.D. Anway. Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors. Ann N Y Acad Sci 2005; 1061: 18-32.
J.M. Swanson, et al. Developmental origins of health and disease: environmental exposures. Semin Reprod Med 2009; 27: 391-402.
M. Szyf. The dynamic epigenome and its implications in toxicology. Toxicol Sci 2007; 100: 7-23.
A. Toren, et al. Pediatric cancer: environmental and genetic aspects. Pediatr Hematol Oncol 1996; 13: 319-331.
T.Y. Zhang & M.J. Meaney. Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol 2010; 61: 439-466, C431-433.
J. Guthman & B. Mansfield. The implications of environmental epigenetics: a new direction for geographic inquiry on health, space, and nature-society relations. Progress in Human Geography 2012; 37: 486-504.
R.P. Arasaradnam, et al. A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 2008; 3: 193-198.
R. Verma, et al. In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components. Toxicol Appl Pharmacol 2011; 253: 178-187.

T. Delport & I. Pollard. Changing perspective on obesity: genetic and environmental health consequences in the offspring. Eubios Journal of Asian and International Bioethics 2010; 20: 170-173.
C. Dupras, et al. Epigenetics and the Environment in Bioethics. Bioethics 2012.
J. Elia, et al. Attention-deficit/hyperactivity disorder genomics: update for clinicians. Curr Psychiatry Rep 2012; 14: 579-589.
M.H. Johnson. The problematic in-vitro embryo in the age of epigenetics. Reprod Biomed Online 2005; 10 Suppl 1: 88-96.
M. Loi, et al. Social Epigenetics and Equality of Opportunity. Public health ethics 2013; 6: 142-153.
M.A. Rothstein, et al. The ghost in our genes: legal and ethical implications of epigenetics. Health Matrix Clevel 2009; 19: 1-62.
M.A. Rothstein, et al. Ethical implications of epigenetics research. Nat Rev Genet 2009; 10: 224.
D. Ziech, et al. The role of epigenetics in environmental and occupational carcinogenesis. Chem Biol Interact 2010; 188: 340-349.
L. Daxinger & E. Whitelaw. Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genet 2012; 13: 153-162.
F. Khan. Preserving human potential as freedom: a framework for regulating epigenetic harms. Health Matrix Clevel 2010; 20: 259-323.
R. Chadwick & A. O'Connor. Epigenetics and personalized medicine: prospects and ethical issues. Personalized Medicine 2013; 10: 463-471.
G. Gestri, et al. Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression. Development 2005; 132: 2401-2413.
M. Hedlund. Epigenetic Responsibility. Medicine Studies 2012; 3: 171-183.
C.J. Weiner. Transgenerational Tort Liability for Epigenetic Disease. DePaul J Health Care L 2010; 13: 319-338.
J. Guthman & B. Mansfield. The implications of environmental epigenetics: a new direction for geographic inquiry on health, space, and nature-society relations. Progress in Human Geography 2012; 37: 486-504.
M. Loi, et al. Social Epigenetics and Equality of Opportunity. Public health ethics 2013; 6: 142-153.

F.F. Costa. Big data in biomedicine. Drug Discov Today 2013.
J. Elia, et al. Attention-deficit/hyperactivity disorder genomics: update for clinicians. Curr Psychiatry Rep 2012; 14: 579-589.
S.D. Kahn. On the future of genomic data. Science 2011; 331: 728-729.