(Ext. 3521)
Thibert, Roger J.; B.A. (Western Ontario), M.S. (Detroit), Ph.D. (Wayne State), F.C.I.C.1953.
McGarvey, Bruce R.; B.A. (Carleton College), M.A., Ph.D. (Illinois), F.C.I.C.1972.
Tuck, Dennis G.; B.Sc., Ph.D., D.Sc. (Durham), F.C.I.C., F.R.S.C. (U.K.)1972.
McKenney, Donald J.; B.Sc., M.Sc. (Western Ontario), Ph.D. (Ottawa)1964.
McIntosh, John M.; B.Sc. (Queen's), Ph.D. (M.I.T.), F.C.I.C.1968.
Drake, John E.; B.Sc., Ph.D., D.Sc. (Southampton), F.C.I.C.1969.
Taylor, Keith E.; B.Sc., Ph.D. (Toronto)1976.
Mutus, Bulent; B.Sc., M.Sc. (Waterloo), Ph.D. (Manitoba)1982.
Stephan, Douglas W.; B.Sc. (McMaster), Ph.D. (Western Ontario)F.C.I.C.1982.
Aroca, Ricardo; B.Sc. (Chile), Ph.D. (Moscow State), D.Sc. (Leningrad)1985.
Loeb, Stephen J.; B.Sc., Ph.D. (Western Ontario)1990.
Jones, William E.; B.Sc., M.Sc. (Mount Allison), Ph.D. (McGill)1991. (Vice-President, Academic)
Szabo, Arthur G.; B.Sc. (Queen's), M.A., Ph.D. (Toronto), F.C.I.C.1994. (Head of the Department)
Rumfeldt, Robert C.; B.Sc. (Loyola, Montreal), Ph.D. (Alberta)1965.
Hencher, J. Lawrence; B.A., Ph.D. (McMaster)1967.
Adeli, Khosrow; B.Sc. (Tehran), M.Sc., Ph.D. (Ottawa), Dipl. Clin. Chem. (Toronto)1988.
Lee, Lana; A.B. (Mount Holyoke), Ph.D. (Alberta)1986.
Green, James R.; B.Sc. (Windsor), Ph.D. (Waterloo)1989.
Christopoulos, Theodore K.; B.Sc., Ph.D. (Athens), Dipl. Clin. Chem.
Dutton, Philip J.; B.Sc., Ph.D. (Victoria)1991.
(Toronto)1992.
Adjunct Professors
Asselstine, Harold S.; B.Sc., M.D. (McGill), F.R.C.P.(C); Medical Director, Medical Laboratories of Windsor1969.
Draisey, Thomas F.; M.B., Ch.B. (Bristol), F.R.C.Path.; Department of Pathology, Hotel Dieu-Grace Hospital and Windsor Western Hospital Centre1969.
Taylor, Norman F.; B.A., M.A., D.Phil. (Oxon), F.R.S.C. (U.K.)1973.
Kovacs, Gregory J.: B.Sc., M.Sc., Ph.D (Toronto)1991.
Nazri, Gholam-Abbas; B.S., M.S. (Tehran), Ph.D. (Case Western Reserve)1991.
Foreback, Craig C.; B.A. (South Florida), Ph.D. (South Florida); Director of Clinical Chemistry, Henry Ford Hospital, Detroit 1986.
Yee, George E.; M.D. (Manitoba), F.R.C.Path.; Director of Pathology Laboratories, Metropolitan General Hospital, Windsor1986.
Cheung, Raphael M.C.; M.D. (Toronto), F.R.C.P.(C); Medical Director, Lipid Clinic, Windsor Western Hospital1988.
Artiss, Joseph D.; B.Sc., Ph.D. (Windsor); Associate Professor of Pathology, Wayne State University and Technical Director - Chemistry, DMC University Laboratories, Detroit1994.
Yee, Hugh; B.S., M.S., Ph.D. (Wayne State); Technical Director - Toxicology, DMC University Laboratories, Detroit1994.
Drury, Craig F.; B.Sc., M.Sc. (McGill), Ph.D. (Guelph); Soil Microbiologist, Agriculture Canada Research Station, Harrow1991.
Sellers, Allyson R.; B.A. (Guelph), B.Ed. (Lakehead), M.D. (McMaster), F.R.C.Path.; Anatomic and General Pathologist, Hotel Dieu Hospital, Windsor1993.
The Department of Chemistry and Biochemistry offers programs leading to the Bachelor of Science degree in Honours Chemistry, Honours Biochemistry, Honours Chemistry and Physics, and general degrees in both Chemistry and Biochemistry. These programs are subject to the regulations of the Faculty as outlined in 5.3.1 and 5.3.2.
Courses are available to permit the student to become fully prepared for entry into medical, dental, and pharmacy schools, as well as graduate programs in the physical and life sciences. Students should determine as early as possible the specific requirements for graduate or professional schools and programs that they may wish to apply for after completing all or part of a Chemistry or Biochemistry program. (See also 5.3.5.) Advisors are available in the Department.
Languages Other Than English: Since many graduate schools have language requirements, students who may subsequently choose to enter graduate school are strongly advised to consider a selection of courses which includes the prominent scientific languages, French, German and Russian.
Community College Graduates: Graduates of three-year programs in Chemical Technology, Environmental Technology, Industrial Hygiene Technology and Medical Technology may be given substantial credit toward degree programs in Chemistry or Biochemistry. Detailed advice on these matters can be obtained from the Department of Chemistry and Biochemistry.
Standing Required: For admission to any Chemistry or Biochemistry program at the second level, a student must obtain a minimum grade of 5.0 in Chemistry 59-140 and 59-141, or the equivalent. Students in Biochemistry also must obtain a minimum grade of 5.0 in Biology 55-140 and 55-141. Furthermore, for admission to and continuation in any honours program a student must have and maintain a minimum major average of 8.0 and a cumulative average of 5.0.
Graduation Requirements: In order to graduate from the general programs in Chemistry or Biochemistry, a student must achieve a major average of 5.0 in all Chemistry courses and a cumulative average of 5.0. In order to graduate from the honours programs in Chemistry, a student must achieve a minimum major average of 8.0 and a cumulative average of 5.0.
The three honours programs offered by the Department of Chemistry and Biochemistry are accredited by the Chemical Institute of Canada.
1) The prerequisite for 59-410 shall normally be a major average of 8.0 or consent of the Department. Students lacking the prerequisite must take two courses, as approved by the Department, in lieu of 59-410.
2) Unless otherwise stated, students in Chemistry and Biochemistry are expected to take the course with laboratory where two offerings differing only in the presence or absence of a laboratory component are listed.
Total courses: thirty.
Major requirements: fifteen courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321 and four other 300- or 400-level courses.
Other requirements:
(a) 62-120, 62-140, 62-141, 64-140, 64-141, and 64-220;
(b) four courses from the Faculties of Arts and Social Science, with at least one from each;
(c) five courses from any department, school, or faculty.(62-215 and 62-216 are strongly recommended.)
RECOMMENDED COURSE SEQUENCE
Level 1: ten courses, including 59-140, 59-141, 62-120, 62-140, 62-141, 64-140, and 64-141. (Recommended: 60-104, or 64-151.)
Level 2: ten courses, including 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, and 64-220.
Level 3: ten courses, including six 300- or 400-level Chemistry and Biochemistry courses. (62-215 abd 62-216 are recommended.)
Total courses: thirty.
Major requirements: fifteen courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321, 59-360, 59-361, and 59-365; plus one additional course at the 300 or 400 level.
Other requirements:
(a) 55-140, 55-141, 55-213, 55-243, 62-140, 62-141, 64-140, and 64-141; plus either 60-104 or 64-151;
(b) four courses from the Faculties of Arts and Social Science, with at least one from each;
(c) two courses from any department, school, or faculty.
RECOMMENDED COURSE SEQUENCE
Level 1: ten courses, including 55-140, 55-141, 59-140, 59-141, 62-140, 62-141, 64-140, and 64-141; plus either 60-104 or 64-151.
Level 2: ten courses, including 55-213, 55-243, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, and 59-261.
Level 3: ten courses, including 59-320, 59-321, 59-360, 59-361, and 59-365; plus another Chemistry and Biochemistry course.
Total courses: forty.
Major requirements: twenty courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321, 59-400, and 59-410 (a 6.0 credit course), and six additional courses at the 300 or 400 level.
Other requirements:
(a) 62-120, 62-140, 62-141, 64-140, 64-141, and 64-220.
(b) four courses from the Faculties of Arts or Social Science with at least one from each;
(c) ten courses from any department, school, or faculty. (62-215 and 62-216 are strongly recommended.)
RECOMMENDED COURSE SEQUENCE
Level 1: ten courses, including 59-140, 59-141, 62-120, 62-140, 62-141, 64-140, 64-141. (Recommended: 60-104 or 64-151.)
Level 2: ten courses, including 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, and 64-220.
Levels 3 and 4: twenty courses, including 59-320, 59-321, 59-400, and 59-410; and six additional Chemistry and Biochemistry courses. (Recommended: 62-215 and 62-216.)
Total courses: forty.
Major requirementsChemistry and Biochemistry: sixteen courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-320, 59-321, 59-330 (or 59-331), 59-342, and 59-400; plus three other courses.
Major requirementsPhysics: fourteen courses, including 64-140, 64-141, 64-151, 64-220, 64-221, 64-222, 64-250, 64-261, 64-310, 64-315, 64-322 (or 64-321), and 64-331; plus two other courses at the 300 or 400 level.
Other requirements:
(a) 62-120, 62-140, 62-141, 62-215, 62-216, and 62-218;
(b) two courses from either of the Faculty of Arts or the Faculty of Social Science;
(c) two courses from any department, school, or faculty.
RECOMMENDED COURSE SEQUENCE
Level 1: ten courses, including 59-140, 59-141, 62-120, 62-140, 62-141, 64-140, 64-141, and 64-151.
Level 2: 59-230, 59-235, 59-240, 59-241, 62-215, 62-216, 62-218, 64-220, 64-221, and 64-222.
Level 3: ten courses, including 59-250, 59-251, 59-342, 64-250, 64-261, 64-310, 64-315, 64-322 (or 64-321), and 64-331.
Level 4: ten courses, including 59-320, 59-321, 59-330 (or 59-331), and 59-400; plus three additional Chemistry courses; and two additional Physics courses at the 300 or 400 level.
Total courses: forty.
Major requirements: twenty courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321, 59-360, 59-361, 59-365, 59-400, and 59-410 (a 6.0 credit course); plus three additional courses at the 300 or 400 level.
Other requirements:
(a) 55-140, 55-141, 55-213, 55-243, 62-140, 62-141, 64-140, 64-141 and 60-104 (or 64-151).
(b) four courses from the Faculties of Arts and Social Science, with at least one from each;
(c) seven courses from any department, school, or faculty.
RECOMMENDED COURSE SEQUENCE
Level 1: ten courses, including 55-140, 55-141, 59-140, 59-141, 62-140, 62-141, 64-140, 64-141, and 60-104 (or 64-151).
Level 2: ten courses, including 55-213, 55-243, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, and 59-261.
Level 3 and Level 4: twenty courses, including 59-320, 59-321, 59-360, 59-361, 59-365, 59-400, 59-410 (a 6.0 credit hour course) and three additional courses from Chemistry and Biochemistry at the 300- or 400-level.
For Faculty of Science regulations, see 5.3.2.
Programs combining Chemistry with another major will consist of the following:
Total courses: forty.
Major requirementsChemistry and Biochemistry: fifteen courses, including 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321, 59-330 (or 59-331), and 59-340; plus two additional courses at the 300- or 400- level.
Major requirementsOther Subject: as prescribed by that department or school.
Other requirements:
(a) 62-120, 62-140, 62-141, 64-140, 64-141, and 64-220;
(b) additional courses, if necessary, from any department, school, or faculty to a total of forty courses.
Programs combining Biochemistry with another major will consist of the following:
Total courses: forty.
Major RequirementsChemistry and Biochemistry: fifteen courses, consisting of 59-140, 59-141, 59-230, 59-235, 59-240, 59-241, 59-250, 59-251, 59-261, 59-320, 59-321, 59-360, 59-361, 59-365, and one additional course at the 300- or 400-level.
Major requirementsOther Subject: as prescribed by that department or school.
Other requirements:
(a) 55-140, 55-141, 55-243, 62-140, 62-141, 64-140, and 64-141;
(b) additional courses, if necessary, from any department, school, or faculty to a total of forty courses.
The minors in Chemistry and in Biochemistry consist of six courses, including 59-140 and 59-141, plus three courses at the 200 level or above, and at least one course at the 300 level or above. If the minor is in Biochemistry, at least three of 59-261, 59-360, 59-361, 59-365, 59-464 and 59-468 must be chosen. Selected courses leading to a minor in either area may not consist of antirequisites to courses in the student's degree program. Where two offerings of a course differing only in the presence or absence of a laboratory are available, students are expected to select the one with the laboratory. Students must also remember to select only courses which may be otherwise counted for credit towards their degree programs.
See Faculty of Science, 5.3.1.
Bachelor of Science
See Faculty of Science, 5.3.1.
All courses listed will not necessarily be offered each year.
The prerequisite of all 200-level courses, unless otherwise indicated, will be both 59-140 and 59-141.
The prerequisite for all 400-level courses will be the consent of the instructor, except as noted.
An introduction to selected topics in modern chemistry for science and engineering: properties of matter and solutions, stoichiometry, equilibrium theory and applications, oxidation-reduction reactions, rate processes, atomic and molecular structure. (Prerequisite: OAC Chemistry.) (3 lecture, 3 laboratory hours a week.)
Introductory concepts in chemistry, including reactions of atoms, ions, and molecules, solution stoichiometry, thermochemistry, electronic structure of atoms, basic chemical bonding and molecular geometry, periodic properties of the elements, and the theory of gases. (Prerequisite: OAC Chemistry or consent of the Department.) (3 lecture, 3 laboratory/tutorial hours a week.)
A continuation of 59-140 covering topics such as chemical kinetics, general equilibrium theory, acid-base theory, chemical thermodynamics, and an introduction to organic chemistry. (Prerequisite: 59-140.) (3 lecture, 3 laboratory/tutorial hours a week.)
A course of particular interest to students of nursing and other health science areas. The subject matter includes a survey of organic functional groups, the organic chemistry of biomolecules, and a survey of the major metabolic pathways. (Prerequisite: OAC Chemistry.) (Antirequisites: 59-141, 59-230, and 59-232.) (2 lecture hours, 1 tutorial hour a week.)
Introduction to organic chemistry, with emphasis on structure, stereochemistry, and reactions of aliphatic and alicyclic compounds and their functionalized derivatives. (Prerequisites: 59-140 and 59-141.) (Antirequisite: 59-232.) (3 lecture, 3 laboratory hours a week.)
The same as 59-230 but without the laboratory. (Prerequisites: 59-140 and 59-141) (Antirequisite: 59-230.) (3 lecture hours a week.) (Not available for credit to students majoring in Chemistry, Biochemistry, or Biological Sciences.)
A continuation of 59-230. Topics include the chemistry of nitrogen-containing compounds, aromatic chemistry and an introduction to spectroscopic methods. (Prerequisite: 59-230.) (2 lecture hours a week.)
The laws of thermodynamics applied to changes of state and chemical reactions. Spontaneous processes. (Prerequisites: 59-140, 62-140, and 62-141.) (3 lecture, 1.5 laboratory hours a week.)
Physical and chemical equilibrium, electrochemistry. (Prerequisite: 59-240.) (3 lecture, 3 laboratory hours a week.)
Introduction to chemical bonding including molecular orbital and valence bond models and their application to the stereochemistry and properties of hydrides and halides. Photoelectron, NMR, and vibrational spectroscopy are introduced as complementary tools in the examination of these molecular species. (3 lecture, 1.5 laboratory hours a week.)
The coordination chemistry of transition metals will be discussed, with particular reference to the means of physical and spectroscopic characterization. Relevance of such compounds to bio-inorganic systems will also be discussed. (Prerequisite: 59-250.) (3 lecture, 3 laboratory hours a week.)
The same as 59-251 but without the laboratory. (Prerequisite: 59-250.) (3 lecture hours a week.)
An extension of the principles covered in 59-230 to the structure and properties of organic molecules of biological significance. (Prerequisite: 59-230.) (3 lecture, 3 laboratory hours a week.)
The same as 59-261 but without the laboratory. (Prerequisites: 59-141 or consent of instructor.) (3 lecture hours a week.) (Not available for credit to students majoring in Chemistry, Biochemistry, or Biological Sciences.)
A course of particular interest to students of nursing and other health science areas. The principles of pharmacokinetics and pharmacodynamics will be covered utilizing a systems approach to pharmacologic therapies in health care. (Prerequisites: 55-204, 55-205, and one of 59-141, 59-191, 59-230 and 59-232.) (2 lecture hours, 1 tutorial hour a week.) (May be taken by B.Sc. students for credit, but does not count as a Biochemistry course towards the fulfillment of the requirements for the B.Sc. degree.)
Solution chemistry. Precipitation, complexation, electron transfer, and proton transfer reactions. Potentiometric, polarographic and amperometric titration techniques. Data analysis and chemical statistics. (Prerequisites: 59-141, 62-141, and 65-253, or consent of instructor.) (3 lecture, 3 laboratory hours a week.)
Electronic and digital circuits. Microprocessor controlled instrumentation and microcomputer interfacing. Data acquisition and data processing in electrochemical and spectroscopic techniques. (Prerequisite: 59-320.) (2 lecture hours, 1 tutorial hour, 3 laboratory hours a week.)
Structure elucidation and the use of spectroscopic techniques in organic chemistry. The laboratory portion focuses on synthetic chemistry, with application of spectroscopic methods. (Prerequisite: 59-235 or consent of instructor.) (3 lecture, 3 laboratory hours a week.)
The methods of organic synthesis and the reaction mechanisms involved. (Prerequisite: 59-235 or consent of instructor.) (3 lecture, 3 laboratory hours a week.)
The same as 59-330 but without the laboratory. (Prerequisite: 59-235 or consent of instructor.) (3 lecture hours a week.)
The same as 59-331 but without the laboratory. (Prerequisite: 59-235 or consent of instructor.) (3 lecture hours a week.)
Collisions, transport properties and rates of chemical reactions. (Prerequisite: 59-241.) (2 lecture, 3 laboratory hours a week.)
Introduction to quantum chemistry, rotational and vibrational spectroscopy of diatomic and polyatomic molecules, visible and ultraviolet and Raman spectroscopy. (Prerequisite: 59-340.) (3 lecture, 3 laboratory hours a week.)
Same as 59-340 but without laboratory. (Prerequisite: 59-241 and consent of instructor.) (2 lecture hours a week.)
The same as 59-341 but without the laboratory. (Prerequisite: 59-340 or 59-342.) (3 lecture hours a week.)
An introduction to main group chemistry. This will start as a continuation of 59-250 and deal with a systematic examination of the structure and reactivity of simple and complex oxides and halides of the main group elements. Additional topics such as main group chains, rings, and cages, non-aqueous solvents and main group organometallic compounds will also be discussed. (Prerequisite: 59-250.) (3 lecture, 3 laboratory hours a week.)
The course will cover the structure, synthesis, spectroscopic properties, and reactivity of transition metal complexes which incorporate M-C and M-H bonds. The principles of bonding and fluxionality, as well as applications of this chemistry in catalytic processes of industrial interest will be discussed. (Prerequisite: 59-251.) (3 lecture, 3 laboratory hours a week.)
The same as 59-350 but without the laboratory. (Prerequisite: 59-250.) (3 lecture hours a week.)
The same as 59-351 but without the laboratory. (Prerequisite: 59-251 or 59-253.) (3 lecture hours a week.)
Catabolism and the generation of phosphate bond energy. Laboratory exercises are associated with the analytical and preparative procedures of biochemistry. (Prerequisite: 59-261.) (3 lectures, 3 laboratory hours a week.)
The utilization of phosphate bond energy will be illustrated by carbohydrate, fatty acid and lipid biosynthesis, hormonal (G-proteins) and metabolite regulation, biological membranes (structure and transport mechanisms) and contractile processes (muscle biochemistry). (Prerequisite: 59-360.) (2 lectures, 3 laboratory hours a week.) (Limited enrolment.)
The same as 59-360 but without the laboratory. (Prerequisite: 59-261 or 59-263.) (3 lecture hours a week.)
The same as 59-361 but without the laboratory. (Prerequisite: 59-360 or 59-362.) (2 lecture hours a week.)
The covalent and three dimensional structures of these macromolecules will be described in conjunction with study of the chemical and physical methods used in their purification and characterization. (Prerequisite: 59-261.) (2 lecture hours a week.)
Discussion of selected topics from the current literature. (1 lecture hour a week over two terms; 3.00 credit hours; under special circumstances may be completed in one term.) (Normally open to students in only Honours Chemistry, Honours Chemistry and Physics, or Honours Biochemistry.)
Original laboratory research under the direction of a faculty member. (1 lecture, 12 laboratory hours a week) (A 6.00 credit hour course given over two terms.) (See above, "Program Requirements".)
Special topics in analytical chemistry. (2 lecture hours a week.)
Topics may include polymer chemistry, natural product chemistry, advanced synthetic methodology, or design and execution of organic syntheses. (Prerequisite: 59-331 or consent of instructor.) (2 lecture hours a week.)
Physical organic chemistry. Includes molecular orbital theory, stereochemistry, thermodynamics, and reaction mechanisms. (Prerequisite: 59-331 or consent of instructor.) (2 lecture hours a week.)
Rates of reaction, theory and mechanisms, solution kinetics and photochemical kinetics. (2 lecture hours a week.)
Development of statistical thermodynamics and its application to theories of gases, condensed states and chemical equilibria. (2 lecture hours a week.)
Special topics in physical chemistry. (2 lecture hours a week.)
Various applications of group theory to the study of organic and inorganic systems. (Prerequisite: 59-341, or 59-343, or consent of instructor.) (2 lecture hours a week.)
Advanced topics in inorganic chemistry and organometallic chemistry may include analytical and spectroscopic methods of use to the inorganic chemist, advanced topics in main group chemistry, coordination chemistry, organometallic chemistry, or the chemistry of the lanthanides and actinides. (Prerequisite: 59-351 or 59-353.) (2 lecture hours a week.)
Mechanisms of enzyme action will be covered in terms of kinetics, functional groups responsible for catalysis and specificity and the design of active-site directed irreversible inhibitors. (2 lecture hours a week.)
(2 lecture hours a week.)
An advanced lecture and laboratory course dealing with DNA science and the application of DNA technology in the understanding and diagnosis of human disease. The lectures cover the biochemistry and expression of DNA and RNA at the molecular level, the theory and practice of recombinant DNA technology, and the application of DNA probes in diagnosis of human disease. The laboratory component involves construction and cloning of a recombinant DNA molecule. (Limited enrolment.)
Perturbation and variation theories. Theories of many electron atoms and general theories of chemical bonds in diatomic and polyatomic molecules. (Prerequisite: 59-341 or 59-343.) (2 lecture hours a week.)
(2 lecture hours a week.)