Filo Viruses

Hugh B. Fackrell

fackrel@Uwindsor.ca

Filename: Filovir.ppt

Filoviruses Outline

• Structure

• Classification

• Multiplication

• Clinical manifestations

• Epidemiology

• Diagnosis

• Control

Baron’s Web Site

PPT Slide

Ebola virus

First photograph 1976

PPT Slide

Ebola virus

PPT Slide

Ebola virus growing in cell

Marburg Virus

Filovirus

• cause disease in humans due to contact with monkeys.

• .......................Ebola virus..........................

• Book “The Hot Zone”

• Movie “Outbreak”

• First recognized in 1976 - Zaire, Kenya,

• ..............Zimbabwe 18% have antibodies

CDC Fact sheet

Filovirus

• Ebola virus

• Fever, hemorrhages from multiple sites, diarrhea,vomiting, myalgia, pharyngitis, conjunctivitis, rash.

• Patient with all symptoms. 90% death rate

• Marburg virus

• Lab workers exposed to monkey tissue.7/25 died.

• Symptoms same as Ebola. The natural reservoir not identified

• Clinical note:pg. 656 Jensen & Wright

DONE!!!