Principles of Disease

Updated 19/02/01

Academic education is the act of memorizing things read in books, and things told by college professors who got their education mostly by memorizing things read in books and told by college professors Elbert Hubbard
	Early Microbiologists!!

Who am I? I was the first to use modern biochemical techniques to work out the detailed biochemistry of the compolement activation process.

	Principles of Disease and Epidemiology
	Mechanisms of Pathogenicity HBF Lecture Host Defenses HBF Lecture
	Baron Medical Microbiology Chapter 1 Immunology Overview		Brock 9th Ed Biology of Microorganisms Chapt 20 Concepts of Immunology Chap 21: Clinical and Diagnostic Microbiology and Immunology
	Tortora: Microbiology An Introduction Chapt 14: Principles of Disease and Epidemiology		Jacquelyn Black 4th Ed Microbiology: Principles & Explorations Chap 16: Nonspecific Host Defenses
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Disease Principles

KEY TERMS:
pathogen	pathology	pathogenesis	carrier
etiology	normal microbiota	normal flora	zoonoses
transient microbiota	microbial antogonism	bacteriocins	contact transmission
symbiosis	commensalism	mutualism	direct contact transmission
parasitism	opportunitistic pathogens	synergism	inderect contact transmission
communicable disease	non communicable disease	incidenceof disease	fomite
prevalance of disease	sporadic disease	endemic disease	droplet transmission
epidemic disease	pandemic disease	acute disease	vehicle transmission
chronic disease	subacute disease	latent disease	vector
herd immunity	emerging infectious disease	local infection	mechanical transmission
systemic infection	generalized infection	focal infection	biological transmission
bacteremia	septicemia	toxemia	nosocomial infection
primary infection	secondary infection	subclinical infection	compromised host
predisposing factor	incubation period	prodromal period	epidemiology
CDC	MMWR	morbidity	mortality
notifiable disease	mortality rate	morbidity rate

Compare commensalism, mutualism and parasitism and give and example of each
Why is the normal microbiota essential for good health?
Compare and contrast normal and transient microbiota with opportunistic microorganisms
Summarize Koch's postulates
Distinguish among sporadic, endemic, epidemic and pandemic diseases with specific examples of each.
List five probable reasons for emergin infectious diseases and name one example for each reason.
Contrast human, animal and non living reservoirs and give an example of each.
Explain four methods of disease transmission
How do direct contact, indirect contact and droplet transmission differ?
Identify four predisposing factors for disease.
Draw and properly label a figure that shows the following stages of a disease: period of decline, prodromal period, period of convalescence, period of illness, and incubation period.
Define epidemiology and describe three types of epidemiological investigations
Identify the function of the CDC.