CHRONIC INFLAMMATORY DISEASES ASSOCIATED WITH HEV-LIKE VASCULATURE | |||
DISEASE | AFFECTED ORGAN |
PLUMP ENDOTHELIUM |
MUCIN-LIKE CAMS ON ENDOTHELIUM* |
Crohn's disease | Gut | + | + |
Diabetes mellitus | Pancreas | + | + |
Graves' disease | Thyroid | + | + |
Hashimoto's thyroiditis | Thyroid | + | + |
Rheumatoid arthritis | Synovium | + | + |
Ulcerative colitis | Gut | + | + |
* Includes GlyCAM-1, MAdCAM-1, and CD34. | |||
SOURCE: Adapted from J. P. Gerard and T. A. Springer, 1995, Immunol. Today 16:449. |